Unmasked& Untamed

Research & Science

The evidence
behind the education.

Neurodivergent women in perimenopause deserve the same rigorous, evidence-based information that has historically been available only to neurotypical women. This page is the evidence base for everything taught here.

Why this matters

Research literacy is a self-advocacy tool.

Many neurodivergent women in perimenopause have been dismissed by healthcare providers who are either unfamiliar with the ND perimenopause intersection or who rely on outdated guidance. The best protection against that dismissal is the ability to read and evaluate the evidence yourself.

The Reading the Research series, 10 videos in the free library, teaches you how to evaluate a study, how to read an abstract, what relative risk actually means, and how to identify when research findings have been misrepresented in the media.

The WHI study is the most consequential example. A 2002 study that was misreported and misapplied, leading to two decades of avoidable suffering for women who were denied HRT on the basis of risk calculations that did not apply to them. Understanding what that study actually showed, and what it did not show, is essential context for any conversation with a healthcare provider about hormone therapy.

Watch the Reading the Research series — free

Curated resources

Key studies and documents.

A curated selection of the most important research and guidance documents relevant to the neurodivergent perimenopause experience.

The British Menopause Society Guidelines

Guidelines

The most current evidence-based guidance on menopause management.

NICE Menopause Guideline (NG23)

Guidelines

UK National Institute for Health and Care Excellence guidelines on menopause diagnosis and management.

Estrogen's Effects on the Serotonergic System (Fink et al.)

Research

The foundational research on how estrogen modulates serotonin, critical context for ND women.

ADHD and Estrogen: Research Overview (Quinn & Madhoo)

Research

The key literature on why ADHD symptoms change across the hormonal lifespan.

The WHI Study: What It Found and Why It Was Misreported

Case Study

Understanding the study that shaped two decades of HRT avoidance, and what it actually showed.

Perimenopause and Neurodivergence: The Emerging Evidence

Overview

Curated summary of the emerging research on the ND perimenopause intersection.

How this platform uses research

The standards we hold.

Every factual claim is sourced to peer-reviewed research or established clinical guidance.

Where evidence is limited or contested, that limitation is named explicitly.

Research on neurodivergent women in perimenopause is extremely limited, where Lia extrapolates from related fields, this is clearly indicated.

No affiliation with supplement companies, pharmaceutical companies, or other commercial healthcare interests.

This platform does not provide medical advice. The research is provided to support informed conversations with healthcare providers.